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The Department of Surgery, Division of Orthopaedics,
sponsors a full Orthopaedic Research Laboratory, which is located
in the basement of the Lyons-Harrison Research Building. The laboratory
assists in any research related to the study of orthopaedics at
UAB, where our focus has been related to biomechanics and biomaterials.
We have four full-time staff members, who are specialists in laboratory
animal technology, histotechnology, soft and hard tissue processing,
scanning electron microscopy, metrology, and implant retrieval analysis.
Our implant retrieval analysis program is aimed at the study of
musculoskeletal reconstructive surgery orthopaedic devices, which
have been explanted during revision surgery. Together with pathologists
and representatives from the Biomedical Engineering Department,
we study biomaterial-to-tissue interfaces, clinical records and
outcomes, device function, engineering material properties and design
features. In this way, we hope to make recommendations for improvements
on future devices and treatments.
We also do outside histology work for researchers who need plastic-embedded
sections, since we have the Exakt cutting and grinding system, which
is designed to produce precision-parallel thin sections of bone
samples containing synthetic material implants. Our lab features
the Micro-Vu system, which is capable of visualization and 3-D coordinate
measurements. We also do SEM-EDAX, image analysis, profilometry
and coordinate measurement. An affiliated laboratory includes facilities
for biomechanical testing (MTS Bionix 858 and Instron machines),
metallography, casting surface modifications and laboratory wear
testing.
The goal of the orthopaedic research laboratory is to facilitate
the three main goals of UAB, which are excellence in education,
research, and patient care service. UAB is the only institution
in the state to have passed the $200 million mark in external research
funding. Ours is one of over seventy special research centers within
UAB which are federally designated in nationally competitive fields.
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